Zu "2081072-29-7" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NEO2734
Artikelnummer: Cay41030-10
NEO2734 is a dual inhibitor of the bromodomain and extra terminal domain family of proteins (BET) and p300/CREB-binding protein (CBP). It binds to bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 (Kds = 3.2, 2.3, and 6.5 nM, respectively), bromodomain testis-specific protein 1 (BRDT1) and BRDT2 (Kds = 3.1 and...
| Schlagworte: | 1,3-dimethyl-5-[2-(tetrahydro-2H-pyran-4-yl)-1-[2-(trifluoromethoxy)ethyl]-1H-benzimidazol-6-yl]-2(1H)-pyridinone |
| Anwendung: | p300/CBP / BET bromodomains dual inhibitor |
| CAS | 2081072-29-7 |
| MW: | 435.4 D |
ab 370,00 €
NEO2734
Artikelnummer: TGM-T8658-100mg
Description: NEO2734 (EP31670) is an orally active, selective inhibitor of p300/CBP and BET bromodomains, with an IC50 of less than 30 nM for both targets. Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: Cc1cc(cn(C)c1=O)-c1ccc2nc(C3CCOCC3)n(CCOC(F)(F)F)c2c1. References: The novel BET-CBP/p300...
| Schlagworte: | EP31670 |
| Anwendung: | p300/CBP / BET bromodomains dual inhibitor |
| CAS | 2081072-29-7 |
| MW: | 435.44 D |
ab 109,00 €
