Zu "2071195-74-7" wurden 2 Artikel gefunden!
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Epertinib (hydrochloride)
Artikelnummer: Cay44442-1
Epertinib is an inhibitor of EGFR, HER2, and HER4 (IC50s = 1.48, 7.15, and 2.49 nM, respectively). It is selective for these kinases over VEGFR2, insulin-like growth factor 1 receptor (IGF-1R), c-Src, KIT, and PDGFRbeta (IC50s = >10,000 nM for all). Epertinib inhibits EGFR and HER2 autophosphorylation in NCI N87...
| Schlagworte: | S-222611, 1-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-butyn-1-one,... |
| Anwendung: | EGFR inhibitor |
| CAS | 2071195-74-7 |
| MW: | 596,48 D |
ab 75,00 €
Epertinib hydrochloride
Artikelnummer: TGM-T11213-100mg
Description: Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Target: EGFR, HER. Smiles:...
| Schlagworte: | S-22611 hydrochloride |
| CAS | 2071195-74-7 |
| MW: | 596.48 D |
ab 79,00 €
