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XL413 hydrochloride
Artikelnummer: TGM-T6735-100mg
Description: XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC 50 of 3.4 nM. XL413 hydrochloride also exhibits potent effect with IC 50 s of 215, 42 nM on CK2, PIM1, respectively, and an EC 50 of 118 nM on pMCM. Target: cholecystokinin, CDK,...
| Schlagworte: | BMS-863233, BMS-863233 Hydrochloride, XL413 |
| Anwendung: | Cdc7 inhibitor |
| CAS | 2062200-97-7 |
| MW: | 326.18 D |
ab 48,00 €
XL413 (hydrochloride)
Artikelnummer: Cay24906-25
XL413 is a potent inhibitor of Cdc7 (IC50 = 3.4 nM). It is >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. XL413 inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively). It inhibits Cdc7-specific phosphorylation of...
| Schlagworte: | 8-chloro-2-(2S)-2-pyrrolidinyl-benzofuro[3,2-d]pyrimidin-4(3H)-one, monohydrochloride |
| Anwendung: | Cdc7 inhibitor |
| CAS | 2062200-97-7 |
| MW: | 326.2 D |
ab 41,00 €
