Zu "2061980-01-4" wurden 2 Artikel gefunden!
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XMU-MP-1
Artikelnummer: TGM-T4212-2mg
Description: XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. Target: Hippo pathway. Smiles: CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12. References: Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med....
| Anwendung: | STK3 / STK4 inhibitor |
| CAS | 2061980-01-4 |
| MW: | 416.48 D |
ab 48,00 €
XMU-MP-1
Artikelnummer: Cay22083-1
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...
| Schlagworte: | 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-benzenesulfonamide |
| Anwendung: | STK3 / STK4 inhibitor |
| CAS | 2061980-01-4 |
| MW: | 416.5 D |
ab 35,00 €
