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Nesuparib
Artikelnummer: Cay45304-1
A dual PARP1/2 and TNKS1/2 inhibitor, reduces the proliferation of Capan-1 PDAC cells (IC50 = 0.1895 µM), selectively inhibits the proliferation of, and induces apoptosis and G2/M phase cell cycle arrest in, HPAF-II and AsPC-1 PDAC cells expressing RNF43 loss-of-function mutations over SNU-410 PDAC cells expressing...
| Schlagworte: | JPI-547, 6-[4-[(1,2,3,4,5,6-hexahydro-5-oxobenzo[h]-1,6-naphthyridin-8-yl)methyl]-1-piperazinyl]-3-pyridinecarbonitrile |
| Anwendung: | Dual PARP1/2 / TNKS1/2 inhibitor |
| CAS | 2055357-64-5 |
| MW: | 400.49 D |
ab 78,00 €
Nesuparib
Artikelnummer: TGM-T61932-100mg
Description: Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourinary disorders, and can be used in the study of neuropathic pain, neurodegenerative...
| Schlagworte: | JPI-547/OCN-201 |
| CAS | 2055357-64-5 |
| MW: | 400.48 D |
ab 85,00 €
