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ML-226
Artikelnummer: Cay25681-1
ML-226 is an inhibitor of alpha/beta hydrolase domain-containing protein 11 (ABHD11) that inhibits ABHD11 in vitro and in situ (IC50s = 15 and 0.68 nM, respectively). It is 100-fold selective for ABHD11 over approximately 20 other serine hydrolases. ML-226 covalently carbamoylates the active site serine of ABHD11....
| Schlagworte: | (2-ethyl-1-piperidinyl)[4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
| Anwendung: | ABHD11 inhibitor |
| CAS | 2055172-43-3 |
| MW: | 390.5 D |
ab 164,00 €
ML-226
Artikelnummer: TGM-T8994-10mg
Description: ML226 is a alpha/beta hydrolase domain-containing protein 11 (ABHD11) inhibitor that inhibits ABHD11 in vitro and in situ. Target: MAGL. Smiles: C(O)(C1=NN(C(=O)N2C(CC)CCCC2)N=C1)(C3=CC=CC=C3)C4=CC=CC=C4. References: Hsu K L , Speers A E , Spicer T , et al. Optimization and characterization of a...
| Schlagworte: | ML-226, ML226 |
| Anwendung: | ABHD11 inhibitor |
| CAS | 2055172-43-3 |
| MW: | 390.48 D |
ab 206,00 €
