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SU 5416
Artikelnummer: Cay13342-50
SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2, FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 µM), SU 5416 also inhibits PDGFR (IC50 = 20 µM),...
| Schlagworte: | NSC 696819, Semaxinib, Sugen 5416, VEGFR 2 Kinase Inhibitor,... |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 204005-46-9 |
| MW: | 238.3 D |
ab 192,00 €
Semaxinib
Artikelnummer: TGM-T2064-100mg
Description: Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 µM), exhibiting a 20-fold greater selectivity for VEGFR2 over PDGFRbeta, with no activity against InsR, EGFR, and FGFR. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting...
| Schlagworte: | SU5416 |
| CAS | 204005-46-9 |
| MW: | 238.28 D |
ab 42,00 €
(E)-3-((3,5-Dimethyl-1H-pyrrol-2- yl)methylene)indolin-2-one
Artikelnummer: CSB-DT2439.1
Amino acids are the basic units of proteins, which are linked by peptide bonds to form polypeptide chains that fold into proteins with specific functions. There are 20 common standard amino acids in nature, primarily distinguished by their side chains (R-groups). These differences give amino acids different...
| CAS | 204005-46-9 |
| MW: | 238.29 D |
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