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HA-1077 (hydrochloride)
Artikelnummer: Cay10010559-10
Rho-associated kinase (ROCK), an effector of the small GTP-binding protein Rho, plays an important role in various cellular functions including vascular smooth muscle contraction, proliferation, and migration as well as inflammatory cell mobility. HA-1077 is a potent inhibitor of ROCK2 and additionally inhibits...
| Schlagworte: | Fasudil, hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine, dihydrochloride |
| Anwendung: | ROCK-II inhibitor |
| CAS | 203911-27-7 |
| MW: | 364.3 D |
ab 67,00 €
Fasudil dihydrochloride
Artikelnummer: TGM-T61382-100mg
Description: Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA/ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 µM, as well as ROCK2, PKA, PKC, and PKG with IC 50 values of 0.158 µM, 4.58 µM, 12.30 µM, and 1.650 µM,...
| CAS | 203911-27-7 |
| MW: | 364.29 D |
ab 150,00 €
