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CADD522
CADD522

Artikelnummer: Cay36679-25

CADD522 is an inhibitor of RUNX family transcription factor 2 (RUNX2) binding to DNA. It inhibits RUNX2 binding to osteoblast-specific element 2 (OSE2) oligonucleotides in a cell-free assay, as well as inhibits RUNX2 enrichment on matrix metalloproteinase-13 (MMP-13) promoters in MCF-7 cells when used at...
Schlagworte: 3-[[(3,4-dichlorophenyl)amino]carbonyl]-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Anwendung: RUNX2-DNA binding inhibitor
CAS 199735-88-1
MW: 326.2 D
ab 69,00 €
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CADD522
CADD522

Artikelnummer: TGM-T8334-100mg

Description: CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity. Target: Others. Smiles: OC(=O)C1C2CC(C=C2)C1C(=O)NC1=CC=C(Cl)C(Cl)=C1. References: Kim MS, et al. Characterization of CADD522, a small molecule that...
Schlagworte: MFCD00167693
Anwendung: RUNX2-DNA binding inhibitor
CAS 199735-88-1
MW: 326.17 D
ab 41,00 €
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