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Baloxavir
Baloxavir

Artikelnummer: TGM-T14495-100mg

Description: Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Target: Influenza Virus. Smiles: Oc1c2C(=O)N3CCOC[C@H]3N([C@@H]3c4ccccc4SCc4c(F)c(F)ccc34)n2ccc1=O. References: Omoto S, et al. Characterization of influenza virus variants induced...
Schlagworte: Baloxavir acid, S-033447
Anwendung: Targets Influenza virus polymerase acidic protein (PA)
CAS 1985605-59-1
MW: 483.49 D
ab 71,00 €
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Baloxavir
Baloxavir

Artikelnummer: LKT-B011458.1

Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
Schlagworte: Baloxavir acid, 4G86Y4JT3F,...
Anwendung: Antiviral, Cap-dependent endonuclease inhibitor
CAS 1985605-59-1
MW: 483.5 D
ab 66,00 €
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Baloxavir
Baloxavir

Artikelnummer: Cay35125-100

Baloxavir is an active metabolite of baloxavir marboxil (Cay-33214). It inhibits influenza virus cap-dependent endonuclease (CEN) and CEN/RNA-dependent RNA polymerase (CEN/RdRp) activities in cell-free assays (IC50s = 2.5 and 1.6 nM, respectively). Baloxavir reduces viral titers in MDCK cells infected with...
Schlagworte: BXA, S-033447,...
Anwendung: Baloxavir marboxil active metabolite
CAS 1985605-59-1
MW: 483.5 D
ab 44,00 €
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