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Bazedoxifene (acetate)
Bazedoxifene (acetate)

Artikelnummer: Cay15005-5

Bazedoxifene (acetate) is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERalpha (IC50 = 26 nM) and ERbeta (IC50 = 99 nM). Bazedoxifene (actetate) antagonizes 17beta-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as...
Schlagworte: TSE 424, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, acetate
Anwendung: Selective estrogen receptor modulator
CAS 198481-33-3
MW: 530.7 D
ab 166,00 €
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Bazedoxifene acetate
Bazedoxifene acetate

Artikelnummer: TGM-T2544-100mg

Description: Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM). Target: Estrogen/progestogen Receptor, Estrogen Receptor/ERR. Smiles: C(=O)(C)O.c1c(cc2c(c1)n(c(c2C)c1ccc(cc1)O)Cc1ccc(cc1)OCCN1CCCCCC1)O. References: Miller CP, et al. J Med Chem, 2001, 44(11), 1654-1657.
Schlagworte: WAY-140424, TSE 424, WAY-TES 424
Anwendung: Osteoporosis agent, Selective estrogen receptor modulator (SERM)
CAS 198481-33-3
MW: 530.67 D
ab 38,00 €
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