Zu "1952236-05-3" wurden 2 Artikel gefunden!
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NEU
MTX-211
Artikelnummer: Cay45142-1
MTX-211 is a dual inhibitor of PI3Kalpha and EGFR (IC50s = <100 nM for both). It reduces viability of 5637, EJ, and UM-UC-3 bladder cancer cells (IC50s = 1.075, 1.514, and 2.189 µM, respectively), an effect that can be partially inhibited by glutathione (GSH). MTX-211 also induces apoptosis, increases the levels of...
| Schlagworte: | N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]-methanesulfonamide |
| Anwendung: | PI3Kalpha/EGFR dual inhibitor |
| CAS | 1952236-05-3 |
| MW: | 478.32 D |
ab 55,00 €
MTX-211
Artikelnummer: TGM-T4296-100mg
Description: MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases. Target: PI3K, EGFR. Smiles: CS(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1. References: Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2
| Schlagworte: | MTX 211 |
| CAS | 1952236-05-3 |
| MW: | 478.33 D |
ab 55,00 €
