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Prinomastat
Artikelnummer: TGM-T12539L-10mg
Description: Prinomastat (AG3340) is an orally active and selective inhibitor of metalloproteinases (MMPs) that crosses the blood-brain barrier. Target: MMP. Smiles: CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1. References: Sørensen MD, et al. Cyclic phosphinamides and phosphonamides, novel series of potent...
| Schlagworte: | KB-R9896, AG3340 |
| Anwendung: | Targets matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] (MMP2) |
| CAS | 192329-42-3 |
| MW: | 423.51 D |
ab 75,00 €
Prinomastat
Artikelnummer: Cay37699-1
Prinomastat is an inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, MMP-9, MMP-13, and MMP-14 (IC50s = 0.05, 0.3, 0.26, 0.03, and 0.33 nM, respectively). It is selective for these MMPs over MMP-1 and MMP-7 (IC50s = 8.3 and 54 nM, respectively). Prinomastat (50 mg/kg) reduces tumor growth and inhibits the...
| Schlagworte: | AG-3340, KB-R9896, (3S)-N-hydroxy-2,2-dimethyl-4-[[4-(4-pyridinyloxy)phenyl]sulfonyl]-3-thiomorpholinecarboxamide |
| Anwendung: | MMP-2 inhibitor |
| CAS | 192329-42-3 |
| MW: | 423.5 D |
ab 41,00 €
