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Danicopan
Artikelnummer: Cay32737-1
Danicopan is an inhibitor of Factor D, a protease in the alternative complement pathway (APC, IC50 = 15 nM in a cell-free assay). It is selective for Factor D over a panel of 12 serine proteases when used at a concentration of 10 µM. Danicopan inhibits hemolysis of erythrocytes isolated from patients with paroxysmal...
| Schlagworte: | ACH-4471,... |
| Anwendung: | Factor D inhibitor |
| CAS | 1903768-17-1 |
| MW: | 580.4 D |
ab 73,00 €
Danicopan
Artikelnummer: TGM-T8509-100mg
Description: Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement...
| Schlagworte: | ACH-4471 |
| Anwendung: | Targets complement factor D [EC:3.4.21.46] (CFD) |
| CAS | 1903768-17-1 |
| MW: | 580.41 D |
ab 91,00 €
