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Firocoxib
Firocoxib

Artikelnummer: Cay28286-10

Firocoxib is a selective inhibitor of COX-2 (IC50s = 0.13 and 7.5 µM for COX-2 and COX-1, respectively, in isolated cat blood). It inhibits LPS-induced production of prostaglandin E2 (PGE2, Cay-14010) in isolated dog, horse, and cat whole blood ex vivo. Firocoxib decreases lameness, induces analgesia, and improves...
Schlagworte: ML-1785713, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
Anwendung: Selective COX-2 inhibitor
CAS 189954-96-9
MW: 336.4 D
ab 67,00 €
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Firocoxib
Firocoxib

Artikelnummer: TGM-T7596-100mg

Description: Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 µM, used for its anti-inflammatory properties in dogs and horses. Target: COX. Smiles: O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3. References: Stock ML, et al. Pharmacokinetics of...
Schlagworte: ML 1785713
Anwendung: Targets prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (PTGS2, COX2)
CAS 189954-96-9
MW: 336.4 D
ab 32,00 €
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