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GSK3787
Artikelnummer: TGM-T1941-100mg
Description: GSK3787 is a specific and irreversible PPARdelta inhibitor(pIC50= 6.6). Target: PPAR. Smiles: FC(F)(F)c1ccc(nc1)S(=O)(=O)CCNC(=O)c1ccc(Cl)cc1. References: Shearer BG, et al. J Med Chem, 2010, 53(4), 1857-1861.
| Anwendung: | PPARbeta/delta antagonist |
| CAS | 188591-46-0 |
| MW: | 392.78 D |
ab 49,00 €
GSK3787
Artikelnummer: Cay15219-5
PPARbeta/delta is thought to play a role in lipid homeostasis and glucose disposal by regulating genes involved in fatty acid oxidation, reverse cholesterol transport, and carbon substrate utilization in skeletal muscle. It has also been implicated in the progression of certain cancers. GSK3787 is an irreversible...
| Schlagworte: | 4-chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-benzamide |
| Anwendung: | PPARbeta/delta antagonist |
| CAS | 188591-46-0 |
| MW: | 392.8 D |
ab 65,00 €
