Zu "1883548-89-7" wurden 3 Artikel gefunden!
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NI-57
Artikelnummer: Cay17662-1
The bromodomain and PHD finger-containing (BRPF) proteins are scaffolding components of chromatin-binding MOZ/MORF histone acetyltransferase complexes, which have activity as transcriptional regulators. BRPF1 (BR140 or Peregrin) is important for maintaining Hox gene expression and the development of multiple...
| Schlagworte: | 4-cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)-2-methoxy-benzenesulfonamide |
| Anwendung: | BRPF bromodomain inhibitor |
| CAS | 1883548-89-7 |
| MW: | 383.4 D |
ab 51,00 €
NI-57
Artikelnummer: TGM-TQ0083-10mg
Description: NI-57 is an inhibitor of the bromodomain and plant homeodomain finger-containing (BRPF) family proteins, with IC50 values of 3.1 nM for BRPF1, 46 nM for BRPF2 (BRD1), and 140 nM for BRPF3. Target: Epigenetic Reader Domain. Smiles: COc1cc(ccc1S(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C#N. References: Igoe N, et...
| Anwendung: | BRPF bromodomain inhibitor |
| CAS | 1883548-89-7 |
| MW: | 383.42 D |
ab 30,00 €
NI-57
Artikelnummer: BPS-82069
NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI-57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI-57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced...
| Schlagworte: | NI57, NI 57, |
| Anwendung: | BRPF bromodomain inhibitor |
| CAS | 1883548-89-7 |
| MW: | 383,4 D |
901,00 €
