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BI-7273
Artikelnummer: TGM-T6783-10mg
Description: BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell. Target: Epigenetic Reader Domain. Smiles: COc1cc(cc(OC)c1CN(C)C)-c1cn(C)c(=O)c2cnccc12. References: Martin LJ, et al. J Med Chem. 2016, 59(10):4462-4475.
| Anwendung: | Cell-permeable BRD9 bromodomain inhibitor |
| CAS | 1883429-21-7 |
| MW: | 353.41 D |
ab 37,00 €
BI-7273
Artikelnummer: Cay20311-1
BI-7273 is a potent BRD9 bromodomain inhibitor (Kd = 15.4 nM, IC50 = 19 nM) that less effectively inhibits the functionally and structurally related BRD7 bromodomain (IC50 = 117 nM). It is without effect against the bromodomains of BRD2 and BRD4, as well as a panel of kinases. BI-7273 inhibits the growth of EOL-1...
| Schlagworte: | 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1(2H)-one |
| Anwendung: | Cell-permeable BRD9 bromodomain inhibitor |
| CAS | 1883429-21-7 |
| MW: | 353.4 D |
ab 52,00 €
