Zu "1874276-76-2" wurden 3 Artikel gefunden!
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LXS-196
Artikelnummer: Cay31455-5
LXS-196 is a PKC inhibitor (IC50s = 1.9 and 0.4 nM for PKCalpha and PKCtheta, respectively). It is selective for PKCalpha and PKCtheta over GSK3beta (IC50 = 3,100 nM). It inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s = 900 and 184 nM, respectively) but not SK-MEL-28 skin...
| Schlagworte: | 3-amino-N-[3-(4-amino-4-methyl-1-piperidinyl)-2-pyridinyl]-6-[3-(trifluoromethyl)-2-pyridinyl]-2-pyrazinecarboxamide |
| Anwendung: | PKC inhibitor |
| CAS | 1874276-76-2 |
| MW: | 472.5 D |
ab 75,00 €
LXS-196
Artikelnummer: LKT-L943721.1
Selective inhibitor of protein kinase C (PKC).
| Schlagworte: | LXS 196, LXS196, NVP-LXS196 |
| Anwendung: | Selective PKC inhibitor |
| CAS | 1874276-76-2 |
| MW: | 472.48 D |
ab 123,00 €
Darovasertib
Artikelnummer: TGM-T5600-100mg
Description: Darovasertib (LXS196) is a potent, selective, and orally active protein kinase C (PKC) inhibitor with IC50 values of 1.9 nM for PKCalpha, 0.4 nM for PKCtheta, and 3.1 µM for GSK3beta. Target: PKC. Smiles: CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F. References: Shoushtari A N , Shoushtari A...
| Schlagworte: | LXS196 |
| Anwendung: | Antineoplastic |
| CAS | 1874276-76-2 |
| MW: | 472.47 D |
ab 46,00 €
