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NEU
XY-018
Artikelnummer: Cay43111-10
XY-018 is an inverse agonist of retinoic acid receptor-related orphan receptor gamma (RORgamma). It induces RORgamma transcriptional activity in a reporter assay using LNCaP cells (IC50 = 0. µM). XY-018 selectively induces RORgamma transcriptional activity over RORalpha transcriptional activity in HEK293T cells...
| Schlagworte: | N-[2'-fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]-2-nitro-benzeneacetamide |
| Anwendung: | ROR gamma inverse agonist |
| CAS | 1873358-87-2 |
| MW: | 516.37 D |
ab 151,00 €
XY018
Artikelnummer: TGM-T24213-2mg
Description: XY 018 is a RORgamma antagonist. It also suppresses androgen receptor expression in prostate cancer cell lines and inhibits the growth of tumors in androgen receptor-positive xenograft models. Target: Others. Smiles: OC(c1ccc(c(F)c1)-c1ccc(NC(=O)Cc2ccccc2[N+]([O-])=O)cc1)(C(F)(F)F)C(F)(F)F. References:...
| Schlagworte: | XY 018, XY-018 |
| CAS | 1873358-87-2 |
| MW: | 516.36 D |
52,00 €
