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IC261
Artikelnummer: LKT-I0801.25
Casein kinase 1 inhibitor.
| Schlagworte: | SU5607, (3E)-3-(2,4,6-Trimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one |
| Anwendung: | Casein kinase 1 inhibitor |
| CAS | 186611-52-9 |
| MW: | 311.12 D |
ab 261,00 €
IC261
Artikelnummer: Cay17260-1
IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1delta and CK1? (IC50 = ~1 µM for both), as well as CK1alpha (IC50 = 16 µM). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC 261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts....
| Schlagworte: | SU5607, 1,3-dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 186611-52-9 |
| MW: | 311.3 D |
ab 49,00 €
NEU
IC261
Artikelnummer: TGM-T2440-100mg
Description: IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 µM and for Cdk5 is 4.5 mM. Target: Apoptosis, CDK, Casein Kinase. Smiles: COc1cc(OC)c(\C=C2\C(=O)Nc3ccccc23)c(OC)c1. References: Behrend L, et al. Oncogene. 2000, 19(47):5303-5313.
| Schlagworte: | SU-5607 |
| CAS | 186611-52-9 |
| MW: | 311.33 D |
ab 60,00 €
