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PD 166326
Artikelnummer: Cay9000988-10
PD 166326 is a pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM). In addition to targeting a select group of receptor tyrosine kinases, PD 166326 also potently inhibits c-src (IC50 = 6 nM). Orally administered PD 166326 is...
| Schlagworte: | 6-(2,6-dichlorophenyl)-2-[[3-(hydroxymethyl)phenyl]amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | Receptor tyrosine kinase inhibitor |
| CAS | 185039-91-2 |
| MW: | 427.3 D |
ab 146,00 €
PD 166326
Artikelnummer: TGM-T22132-100mg
Description: PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2]. Target: Others. Smiles: O=C1C(=CC=2C(N1C)=NC(NC3=CC(CO)=CC=C3)=NC2)C4=C(Cl)C=CC=C4Cl
| Anwendung: | Receptor tyrosine kinase inhibitor |
| CAS | 185039-91-2 |
| MW: | 427.28 D |
ab 1.080,00 €
