Zu "1849603-72-0" wurden 2 Artikel gefunden!
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SBI-553
Artikelnummer: TGM-T16860-100mg
Description: SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 µM). Target: Neurotensin Receptor. Smiles: COc1ccccc1C1CCN(CC1)c1nc(nc2ccc(cc12)N(C)CCO)C1(F)CC1. References: Pinkerton AB, et al. Discovery of beta-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin...
| Anwendung: | beta-arrestin-biased positive allosteric NTSR1 modulator |
| CAS | 1849603-72-0 |
| MW: | 450.55 D |
ab 91,00 €
SBI-553
Artikelnummer: Cay36782-10
SBI-553 is a beta-arrestin-biased positive allosteric modulator (PAM) of neurotensin receptor 1 (NTSR1). It binds to NSTR1 and increases neurotensin-1 affinity for NSTR1 in HEK293 cells expressing the human receptor when used at concentrations ranging from 0.01 to 10 µM. SBI-553 (0.03-30 µM) induces beta-arrestin...
| Schlagworte: | 2-[[2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)-1-piperidinyl]-6-quinazolinyl]methylamino]-ethanol |
| Anwendung: | beta-arrestin-biased positive allosteric NTSR1 modulator |
| CAS | 1849603-72-0 |
| MW: | 450.6 D |
ab 45,00 €
