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PD 153035 (hydrochloride)
Artikelnummer: Cay14879-10
Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR) has been associated with cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. PD 153035 is a highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM, IC50 = 29 pM)....
| Schlagworte: | AG-1517, N-(3-bromophenyl)-6,7-dimethoxy-4-quinazolinamine, monohydrochloride |
| Anwendung: | EGFR inhibitor |
| CAS | 183322-45-4 |
| MW: | 396.7 D |
ab 95,00 €
PD153035 hydrochloride
Artikelnummer: TGM-T1761-100mg
Description: PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM), few influence against FGFR, PGDFR, InsR, CSF-1, and Src. Target: EGFR. Smiles: Cl.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC. References: Fry DW, et al. Science. 1994, 265(5175), 1093-1095.
| Schlagworte: | Tyrphostin AG 1517, SU 5271, AG 1517, ZM 252868 HCl, PD153035 HCl, ZM 252868 |
| Anwendung: | EGFR inhibitor |
| CAS | 183322-45-4 |
| MW: | 396.67 D |
ab 30,00 €
