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RA839
Artikelnummer: Cay42640-1
RA839 is an inhibitor of the protein-protein interaction between Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor erythroid 2-related factor 2 (Nrf2). It binds non-covalently to the Keap1 Kelch domain (Kd = ~6 µM). RA839 increases Nrf2-dependent transcription driven by antioxidant response element...
| Schlagworte: | 1-[4-[[(2,3,5,6-tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid |
| Anwendung: | Keap1-Nrf2 protein-protein interaction inhibitor |
| CAS | 1832713-02-6 |
| MW: | 452.57 D |
ab 35,00 €
RA-839
Artikelnummer: TGM-T28497-10mg
Description: RA-839 is a potent small molecule Keap1 conjugate and selective Nrf2 signalling activator, as well as an inhibitor of Keap1/Nrf2 interaction with anticancer activity.RA-839 inhibits the expression of inducible nitric oxide synthase and inhibits nitric oxide release. Target: Nrf2. Smiles:...
| Schlagworte: | RA 839, RA839 |
| CAS | 1832713-02-6 |
| MW: | 452.57 D |
ab 125,00 €
