Zu "1825302-42-8" wurden 2 Artikel gefunden!
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H3B-8800
Artikelnummer: TGM-T77595-1mg
Description: H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia. Target: Others. Smiles: O(C(=O)N1CCN(C)CC1)[C@H]2/C=C/[C@H](C)[C@@H](\C(=C\C=C\[C@@H](C)C3=CC=CC=N3)\C)OC(=O)C[C@H](O)CC[C@@]2(C)O. References: Rioux N, et al. Metabolic disposition of H3B-8800, an orally available...
| CAS | 1825302-42-8 |
| MW: | 555.71 D |
ab 280,00 €
H3B-8800
Artikelnummer: Cay42106-1
An inhibitor of the SF3B complex, binds to SF3B complexes containing wild-type SF3B (IC50 = 1.4 nM) or various SF3B mutations (IC50s = 0.3-1.8 nM), inhibits SF3B1-induced splicing of canonical and aberrant pre-mRNA junctions in HEK293T nuclear extracts overexpressing SF3B1K700E, selectively inhibits the growth of,...
| Schlagworte: | 4-methyl-1-piperazinecarboxylic acid,... |
| Anwendung: | SF3B complex inhibitor |
| CAS | 1825302-42-8 |
| MW: | 555.71 D |
ab 177,00 €
