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Lomitapide
Artikelnummer: Cay10009610-1
Lomitapide is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 0.5 nM in a triglyceride transfer assay). It inhibits apolipoprotein B (ApoB) secretion in HepG2 cells (EC50 = 0.8 nM). Lomitapide inhibits triglyceride secretion in fasted rats (ED50 = 0.19 mg/kg, p.o.) and reduces total plasma...
| Schlagworte: | AEGR 773, BMS 201038,... |
| Anwendung: | MTTP inhibitor |
| CAS | 182431-12-5 |
| MW: | 693.7 D |
ab 49,00 €
Lomitapide
Artikelnummer: TGM-T6267-100mg
Description: Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density...
| Schlagworte: | AEGR-733, BMS-201038 |
| Anwendung: | Targets microsomal triglyceride transfer protein large subunit (MTTP, MTP) |
| CAS | 182431-12-5 |
| MW: | 693.72 D |
ab 56,00 €
