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SPHINX31
Artikelnummer: Cay21582-5
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50 = 5.9 nM). It is selective for SRPK1 over a panel of 50 kinases at a concentration of 1 µM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), an SRPK1 substrate, in PC3 cells (EC50 = 360 nM) and...
| Schlagworte: | 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide |
| Anwendung: | SRPK1 inhibitor |
| CAS | 1818389-84-2 |
| MW: | 507.5 D |
ab 56,00 €
SPHINX31
Artikelnummer: TGM-T5194-100mg
Description: SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50: 5.9 nM). Target: Serine/threonin kinase. Smiles: FC(F)(F)c1ccc(N2CCN(Cc3ccccn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1. References: Batson J, et al. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical...
| Anwendung: | SRPK1 inhibitor |
| CAS | 1818389-84-2 |
| MW: | 507.51 D |
ab 33,00 €
