Zu "1818314-88-3" wurden 2 Artikel gefunden!

Für die Filterung wurden keine Ergebnisse gefunden!
BMS-1166
BMS-1166

Artikelnummer: TGM-T5697-100mg

Description: BMS-1166 is a potent inhibitor of the PD-1/PD-L1 interaction. Target: PD-1/PD-L1. Smiles: Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1. References: Skalniak L , Zak K M , Guzik K , et al. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the...
Anwendung: PD-1/PD-L1 interaction inhibitor
CAS 1818314-88-3
MW: 641.11 D
ab 88,00 €
Bewerten
BMS 1166
BMS 1166

Artikelnummer: Cay31441-5

BMS 1166 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 1.4 nM in a homologous time-resolved fluorescence (HTRF) assay. It increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1...
Schlagworte: (4R)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl...
Anwendung: PD-1/PD-L1 interaction inhibitor
CAS 1818314-88-3
MW: 641.1 D
ab 92,00 €
Bewerten