Zu "181223-80-3" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
DEL-22379
Artikelnummer: TGM-T6818-100mg
Description: DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ~0.5 µM. Target: Apoptosis, ERK. Smiles: COc1ccc2[nH]cc(C=C3C(=O)Nc4ccc(NC(=O)CCN5CCCCC5)cc34)c2c1. References: Herrero A, et al. Cancer Cell. 2015, 28(2), 170-182.
| Schlagworte: | DEL22379 |
| CAS | 181223-80-3 |
| MW: | 444.53 D |
ab 31,00 €
DEL-22379
Artikelnummer: Cay22433-10
DEL-22379 is an inhibitor of ERK dimerization that disrupts EGF-induced co-immunoprecipitation of ERK tagged with hemagglutinin (HA) or FLAG epitopes with an IC50 value of approximately 0.5 µM without affecting ERK phosphorylation or kinase activity (IC50s = >10 µM). It inhibits cell growth in a panel of melanoma...
| Schlagworte: | N-[2,3-dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide |
| Anwendung: | ERK dimerization inhibitor |
| CAS | 181223-80-3 |
| MW: | 444.5 D |
ab 133,00 €
