Zu "1802148-05-5" wurden 3 Artikel gefunden!
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AZD 7986
Artikelnummer: Cay33184-10
AZD 7986 is a reversible and covalent inhibitor of dipeptidyl peptidase 1 (DPP-1), also known as cathepsin C (IC50 = 3.9 nM). It is selective for DPP-1 over cathepsins S, -L, -B, -K, -D, -E, -Z, -H, and -G (IC50s = >20 µM for all), as well as a panel of greater than 200 enzymes, receptors, ion channels, and...
| Schlagworte: | Brensocatib, INS1007,... |
| Anwendung: | CTSC inhibitor |
| CAS | 1802148-05-5 |
| MW: | 420.5 D |
ab 128,00 €
Brensocatib
Artikelnummer: TGM-TQ0038-10mg
Description: Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively). Target: Proteasome. Smiles: Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1. References: Doyle K, et al. Discovery of Second...
| Schlagworte: | AZD7986, INS 1007 |
| Anwendung: | Targets cathepsin C [EC:3.4.14.1] (CTSC) |
| CAS | 1802148-05-5 |
| MW: | 420.46 D |
ab 49,00 €
Brensocatib
Artikelnummer: BPS-83748-1
Brensocatib, also known as AZD7986 is an oral DPPI (dipeptidyl peptidase 1, also known as cathepsin C) inhibitor. It is being studied for the treatment of bronchiectasis. Cathepsin C, also known as DPPI, is a lysosomal aspartic protease with dipeptidylpeptidase activity over a broad range of substrates. It is mostly...
| Anwendung: | Biochemical, cellular assays |
| CAS | 1802148-05-5 |
| MW: | 420.46 D |
ab 442,00 €
