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CA-4948
Artikelnummer: TGM-T9027-100mg
Description: CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity. Target: IRAK, FLT. Smiles: Cc1cc(ccn1)-c1nc(co1)C(=O)Nc1cc2oc(nc2nc1N1CC[C@@H](O)C1)N1CCOCC1. References: Wiese MD, et al. Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis. Expert Opin...
| Schlagworte: | Emavusertib |
| Anwendung: | Targets interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] (IRAK4) |
| CAS | 1801344-14-8 |
| MW: | 491.5 D |
ab 31,00 €
Emavusertib
Artikelnummer: Cay36845-5
Emavusertib is an inhibitor of IL-1 receptor-associated kinase 4 (IRAK4, IC50 = 31.7 nM). It is selective for IRAK4 over FMS-related tyrosine kinase 3 (FLT3), cyclin-dependent kinase 2 (Cdk2), Aurora A kinase, glycogen synthase kinase 3beta (GSK3beta), and muscle-associated receptor tyrosine kinase (MUSK) at 1 µM....
| Schlagworte: | CA-4948,... |
| Anwendung: | IRAK4 inhibitor |
| CAS | 1801344-14-8 |
| MW: | 491.5 D |
ab 67,00 €
