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BAY-876
Artikelnummer: TGM-T3713-10mg
Description: BAY-876 is an orally active, selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM), exhibiting over 130-fold greater selectivity for GLUT1 than GLUT2, GLUT3, and GLUT4. It also inhibits glycolytic metabolism and ovarian cancer growth. Target: transporter. Smiles:...
| Anwendung: | GLUT1 inhibitor |
| CAS | 1799753-84-6 |
| MW: | 496.42 D |
ab 57,00 €
BAY-876
Artikelnummer: Cay19961-1
BAY-876 is a potent and selective inhibitor of glucose transporter 1 (Glut1) with IC50 values of 2, 10,800, 1,670, and 290 nM for Glut1, Glut2, Glut3, and Glut4, respectively, in CHO cells expressing human recombinant receptors. It shows low metabolic clearance and has high permeability in vitro. In vivo, BAY-876...
| Schlagworte: | N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide |
| Anwendung: | GLUT1 inhibitor |
| CAS | 1799753-84-6 |
| MW: | 496.4 D |
ab 52,00 €
