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LLY-507
Artikelnummer: TGM-T6879-100mg
Description: LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2. Target: Histone Methyltransferase. Smiles: Cc1cn(CCN2CCN(CC2)c2ccccc2-c2cc(cc(c2)C(=O)NCCCN2CCCC2)C#N)c2ccccc12. References: Nguyen H, et al. J Biol Chem. 2015, 290(22):13641-53.
| Schlagworte: | LLY507, LLY 507 |
| Anwendung: | SMYD2 inhibitor |
| CAS | 1793053-37-8 |
| MW: | 574.76 D |
ab 38,00 €
LLY-507
Artikelnummer: Cay16441-1
SMYD2 is a lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53 and retinoblastoma-associated protein. LLY-507 is a cell-active, small molecule inhibitor of SMYD2 (IC50 = 15 nM). It has been shown to inhibit p53 lysine370 monomethylation in KYSE-150 esophageal squamous...
| Schlagworte: | 5-cyano-2'-[4-[2-(3-methyl-1H-indol-1-yl)ethyl]-1-piperazinyl]-N-[3-(1-pyrrolidinyl)propyl]-[1,1'-biphenyl]-3-carboxamide |
| Anwendung: | SMYD2 inhibitor |
| CAS | 1793053-37-8 |
| MW: | 574.8 D |
ab 78,00 €
