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Remibrutinib
Artikelnummer: Cay44962-10
Remibrutinib is a covalent inhibitor of Bruton's tyrosine kinase (BTK. IC50 = 1. nM). It selectively binds to BTK over bone marrow tyrosine kinase on chromosome X (BMX) and Tec (Kds = 0. 540, and 110 nM, respectively), as well as IL-2-inducible T cell kinase (Itk), EGFR, HER2, HER4, and JAK3 (Kds = >10,000 nM for...
| Schlagworte: | LOU064,... |
| Anwendung: | BTK inhibitor |
| CAS | 1787294-07-8 |
| MW: | 507.54 D |
ab 93,00 €
Remibrutinib
Artikelnummer: TGM-T16730-100mg
Description: Remibrutinib inhibits BTK activity with an IC50 value of 0.023 µM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment. Target: BTK. Smiles:...
| Anwendung: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| CAS | 1787294-07-8 |
| MW: | 507.53 D |
ab 93,00 €
