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CRT0066101 (hydrochloride)
Artikelnummer: Cay15337-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
| Schlagworte: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
| Anwendung: | PKD inhibitor |
| CAS | 1781742-22-0 |
| MW: | 447.8 D |
ab 52,00 €
CRT0066101 . HCl
Artikelnummer: AG-CR1-3550-M001
CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2 and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCalpha, PKBalpha, MEK, ERK, c-Raf, c-Src and c-Abl. PKD family members play an important role in regulating...
| Schlagworte: | 2-[4-[[(2R)-2-Aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol . hydrochloride |
| Anwendung: | Protein kinase D (PKD1 / PKD2 / PKD3) inhibitor |
| CAS | 1781742-22-0 |
| MW: | 447.8 D |
50,00 €
CRT0066101 hydrochloride
Artikelnummer: TGM-T84405-10mg
Description: Protein kinase D (PKD), a serine/threonine protein kinase activated by diacylglycerol downstream of PKC signaling, has three human isoforms that modulate cell proliferation, survival, invasion, and protein transport. CRT0066101 acts as an inhibitor of these three PKD isoforms, with IC50 values of 1,...
| Anwendung: | Protein kinase D (PKD1 / PKD2 / PKD3) inhibitor |
| CAS | 1781742-22-0 |
| MW: | 374.87 D |
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