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CRT0066101 . HCl
Artikelnummer: AG-CR1-3550-M001
CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2 and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCalpha, PKBalpha, MEK, ERK, c-Raf, c-Src and c-Abl. PKD family members play an important role in regulating...
| Schlagworte: | 2-[4-[[(2R)-2-Aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol . hydrochloride |
| Anwendung: | Protein kinase D (PKD1 / PKD2 / PKD3) inhibitor |
| CAS | 1781742-22-0 |
| MW: | 447.8 D |
50,00 €
CRT0066101 (hydrochloride)
Artikelnummer: Cay15337-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
| Schlagworte: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
| Anwendung: | PKD inhibitor |
| CAS | 1781742-22-0 |
| MW: | 447.8 D |
ab 46,00 €
