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Ambrisentan
Artikelnummer: TGM-T1655-10mg
Description: Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but has yet to be implicated in cases of clinically apparent acute liver injury. Target:...
| Schlagworte: | BSF 208075, BSF-208075, LU 208075 |
| Anwendung: | Targets endothelin receptor type A (EDNRA) |
| CAS | 177036-94-1 |
| MW: | 378.42 D |
ab 31,00 €
Ambrisentan
Artikelnummer: Cay23669-5
Ambrisentan is a nonpeptide endothelin A (ETA) receptor antagonist (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively). It inhibits contraction of isolated rabbit aortic rings induced by endothelin-1 (ET-1, Cay-24127) by 43.23% when...
| Schlagworte: | alphaS-[(4,6-dimethyl-2-pyrimidinyl)oxy]-beta-methoxy-beta-phenyl-benzenepropanoic acid |
| Anwendung: | Endothelin A (ETA) receptor antagonist |
| CAS | 177036-94-1 |
| MW: | 378.4 D |
ab 44,00 €
