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Sodium 4-Phenylbutyrate
Artikelnummer: Cay11323-1
Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins. It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors. Formulations containing sodium...
| Schlagworte: | Benzenebutanoic Acid, NSC 657802, TriButyrate, benzenebutanoic acid, monosodium salt |
| Anwendung: | Chemical chaperone, HDAC inhibitor |
| CAS | 1716-12-7 |
| MW: | 186.2 D |
ab 41,00 €
Sodium 4-phenylbutyrate
Artikelnummer: TGM-T1535-100mg
Description: Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, increased cell differentiation, and the induction of apoptosis in susceptible tumor...
| Schlagworte: | Sodium Phenylbutyrate, TriButyrate, Buphenyl |
| Anwendung: | Antihyperammonemic, Nitrogen binding agent |
| CAS | 1716-12-7 |
| MW: | 186.18 D |
ab 40,00 €
Phenylbutyrate
Artikelnummer: LKT-P2815.1
An aromatic fatty acid that induces cytostasis, differentiation and apoptosis in primary myeloid leukemic cells, human prostate cancer cell lines and human colon carcinoma cells. It also has chemopreventive effects against chemically induced colon carcinogenesis in experimental animals.
| Anwendung: | Chemopreventive agent |
| CAS | 1716-12-7 |
| MW: | 186,18 D |
ab 120,00 €
