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Zegocractin
Artikelnummer: TGM-TQ0033-100mg
Description: Zegocractin (CM-4620) is an inhibitor of calcium-release activated calcium (CRAC) channels. Target: Calcium Channel. Smiles: Cc1cccc(F)c1C(=O)Nc1cnc(cn1)-c1cc2OC(F)(F)Oc2cc1Cl. References: ARYL SULFONOHYDRAZIDES. WO2016/138472Al.
| Schlagworte: | CM4620, N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide, CM-4620 |
| CAS | 1713240-67-5 |
| MW: | 421.76 D |
ab 121,00 €
CM-4620
Artikelnummer: Cay41977-10
An inhibitor of Orai1/STIM1-containing SOCs (IC50 = 120 nM), selective for Orai1/STIM1-containing SOCs over Orai2/STIM2-containing SOCs (IC50 = 900 nM), decreases cholecystokinin- or taurolithocholic acid 3-sulfate-induced cell death in isolated mouse, rat, and human acini at 3 µM, reduces blood amylase and lipase...
| Schlagworte: | Zegrocractin, N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyrazinyl]-2-fluoro-6-methyl-benzamide |
| Anwendung: | Orai1/STIM1-containing SOC (store-operated calcium channel) inhibitor |
| CAS | 1713240-67-5 |
| MW: | 421.8 D |
ab 116,00 €
