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Donitriptan (hydrochloride)
Donitriptan (hydrochloride)

Artikelnummer: Cay44116-1

Donitriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D. It inhibits forskolin-induced cAMP formation in C6 cells expressing the human receptors (pD2 = 8.91 and 9.57, respectively). Donitriptan is selective for 5-HT1B and 5-HT1D (Kis = 0.36 and 0.15 nM, respectively, for the human...
Schlagworte: F 11356, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-benzonitrile, monohydrochloride
Anwendung: 5-HT1B / 5-HT1D agonist
CAS 170911-68-9
MW: 439,94 D
ab 54,00 €
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Donitriptan hydrochloride
Donitriptan hydrochloride

Artikelnummer: TGM-T21666-100mg

Description: Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively. Target: 5-HT Receptor. Smiles: Cl.N#CC1=CC=C(C=C1)N2CCN(C(=O)COC=3C=CC=4NC=C(C4C3)CCN)CC2. References: Muñoz-Islas E, et al. Donitriptan, but not...
Schlagworte: Donitriptan monohydrochloride, Donitriptan HCl
CAS 170911-68-9
MW: 439.94 D
ab 33,00 €
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