Zu "1708971-72-5" wurden 2 Artikel gefunden!
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FGFR4-IN-1
Artikelnummer: Cay21342-5
FGFR-IN-1 is an inhibitor of FGF receptor 4 (FGFR4, IC50 = 1.3 nM). It is selective for FGFR4 over FGFR1 and a panel of 36 kinases (IC50s = >10 µM for all). It inhibits proliferation of Hep3B and Huh7 hepatic cancer cells with IC50 values of 1.1 and 2.5 nM, respectively. FGFR-IN-1 reduces tumor growth by 62.7 and...
| Schlagworte: | N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(3-oxo-4-morpholinyl)methyl]-1,8-naphthyridine-1... |
| Anwendung: | FGFR-4 inhibitor |
| CAS | 1708971-72-5 |
| MW: | 493.5 D |
ab 56,00 €
FGFR4-IN-1
Artikelnummer: TGM-TQ0256-10mg
Description: FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM). Target: FGFR. Smiles: COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N. References: Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO 2015059668 A1
| Anwendung: | FGFR-4 inhibitor |
| CAS | 1708971-72-5 |
| MW: | 493.52 D |
ab 42,00 €
