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Roblitinib
Artikelnummer: TGM-T4235-100mg
Description: Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine...
| Schlagworte: | FGF-401 |
| Anwendung: | FGFR4 inhibitor |
| CAS | 1708971-55-4 |
| MW: | 506.56 D |
ab 54,00 €
FGF401
Artikelnummer: Cay23029-5
FGF401 is an inhibitor of FGF receptor 4 (FGFR4, IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also...
| Schlagworte: | Roblitinib,... |
| Anwendung: | FGFR4 inhibitor |
| CAS | 1708971-55-4 |
| MW: | 506.6 D |
ab 53,00 €
