Zu "1708113-43-2" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
ACY-1083
Artikelnummer: Cay30505-1
An HDAC6 inhibitor (IC50 = 3 nM), increases the levels of acetylated alpha-tubulin in SK-N-BE(2) cells in a concentration-dependent manner, prevents cisplatin-induced decreases in mitochondrial OCR and mitochondrial motility in tibial nerves isolated from mice at 10 mg/kg per day, inhibits cisplatin-induced...
| Schlagworte: | 2-[(4,4-difluoro-1-phenylcyclohexyl)amino]-N-hydroxy-5-pyrimidinecarboxamide |
| Anwendung: | HDAC6 inhibitor |
| CAS | 1708113-43-2 |
| MW: | 348.4 D |
ab 192,00 €
ACY-1083
Artikelnummer: TGM-T10244-100mg
Description: ACY-1083 is a selective, brain-penetrating HDAC6 inhibitor (IC50: 3 nM) that effectively reverses chemotherapy-induced peripheral neuropathy. Target: HDAC. Smiles: ONC(=O)c1cnc(NC2(CCC(F)(F)CC2)c2ccccc2)nc1. References: Krukowski K, et al. HDAC6 inhibition effectively reverses chemotherapy-induced...
| CAS | 1708113-43-2 |
| MW: | 348.35 D |
ab 146,00 €
