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Nepicastat (hydrochloride)
Nepicastat (hydrochloride)

Artikelnummer: Cay22126-1

Nepicastat is an inhibitor of dopamine beta-hydroxylase (DBH, IC50 = 9 nM for the purified human enzyme). It is selective for DBH over a panel of 12 enzymes and 13 neurotransmitter receptors (IC50s or Kis = >10 µM). Nepicastat dose-dependently reduces norepinephrine content and increases dopamine content in the...
Schlagworte: RS 25560-197, 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione,...
Anwendung: DBH inhibitor
CAS 170151-24-3
MW: 331.8 D
ab 53,00 €
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Nepicastat hydrochloride
Nepicastat hydrochloride

Artikelnummer: TGM-T6604-100mg

Description: Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-beta-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicastat for twelve other enzymes and thirteen neurotransmitter receptors is negligible....
Schlagworte: Nepicastat (SYN-117) HCl, Nepicastat HCl, RS-25560-197 hydrochloride, SYN-117 hydrochloride
Anwendung: DBH inhibitor
CAS 170151-24-3
MW: 331.81 D
ab 49,00 €
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