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IPI-549
Artikelnummer: Cay26416-1
IPI-549 is an inhibitor of PI3Kgamma (IC50s = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). It is greater than 100-fold selective for PI3Kgamma over a panel of 468 mutant and nonmutant protein and lipid kinases, including Class II PI3K isoforms, and a panel of 80 G...
| Schlagworte: | 2-amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]-pyrazolo[1,5-... |
| Anwendung: | PI3Kgamma inhibitor |
| CAS | 1693758-51-8 |
| MW: | 528.6 D |
ab 54,00 €
IPI-549
Artikelnummer: LKT-I611325.100
Selective inhibitor of the gamma isoform of PI3K (PI3Kgamma).
| Schlagworte: | IPI 549, IPI549 |
| Anwendung: | PI3Kgamma inhibitor |
| CAS | 1693758-51-8 |
| MW: | 528.58 D |
ab 180,00 €
Eganelisib
Artikelnummer: TGM-T5432-100mg
Description: Eganelisib (IPI-549) is an inhibitor of PI3Kgamma (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). Target: PI3K. Smiles: C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cnn(C)c3)c2c(=O)n1-c1ccccc1. References: De Vera AA1, Gupta P.et...
| Schlagworte: | IPI-549 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG) |
| CAS | 1693758-51-8 |
| MW: | 528.56 D |
ab 39,00 €
