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RS 67333 (hydrochloride)
Artikelnummer: Cay45937-10
RS 67333 is an agonist of the serotonin (5-HT) receptor subtype 5-HT4. It selectively binds to 5-HT4 (Ki = 2 nM) over 5-HT1A, 5-HT2A, 5-HT2C, and 5-HT3 receptors (Kis = 398, 501, 794, and 398 nM, respectively), as well as alpha- and beta-adrenergic and muscarinic receptors (Kis = >200 nM for all). It also binds to...
| Schlagworte: | 1-(4-amino-5-chloro-2-methoxyphenyl)-3-(1-butyl-4-piperidinyl)-1-propanone, monohydrochloride |
| Anwendung: | 5-HT4 receptor agonist |
| CAS | 168986-60-5 |
| MW: | 389.36 D |
ab 124,00 €
RS 67333 hydrochloride
Artikelnummer: TGM-T23265-10mg
Description: RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1 and D2, and muscarinic M1-M3...
| Schlagworte: | RS 67333 (hydrochloride), RS 67333 HCl |
| CAS | 168986-60-5 |
| MW: | 389.36 D |
ab 30,00 €
