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SGC707
Artikelnummer: TGM-T3084-100mg
Description: SGC707 is a potent, selective, and cell-active allosteric inhibitor of [PRMT3]. Target: Histone Methyltransferase. Smiles: O=C(NCC(=O)N1CCCC1)Nc1ccc2cnccc2c1. References: Kaniskan HÜ, et al. Angew Chem Int Ed Engl. 2015 Apr 20,54(17):5166-70.
| Anwendung: | PRMT3 inhibitor |
| CAS | 1687736-54-4 |
| MW: | 298.34 D |
ab 60,00 €
SGC707
Artikelnummer: Cay17017-1
Protein arginine N-methyltransferase 3 (PRMT3, Cay-11642) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural...
| Schlagworte: | N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea |
| Anwendung: | PRMT3 inhibitor |
| CAS | 1687736-54-4 |
| MW: | 298.3 D |
ab 44,00 €
