Zu "1674364-87-4" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
DS-437
Artikelnummer: Cay29476-1
DS-437 is a dual inhibitor of protein arginine methyltransferase 5 (PRMT5) and PRMT7 (IC50s = 5.9 and 6 µM, respectively). It is selective for PRMT5 and PRMT7 over a panel of 29 additional protein, DNA, and RNA methyltransferases at 50 µM, but also inhibits DNMT3A and DNMT3B (IC50s = 52 and 62 µM, respectively)....
| Schlagworte: | 5'-S-[2-[[(ethylamino)carbonyl]amino]ethyl]-5'-thio-adenosine |
| Anwendung: | PRMT5 / PRMT7 dual inhibitor |
| CAS | 1674364-87-4 |
| MW: | 397.5 D |
ab 54,00 €
DS-437
Artikelnummer: TGM-T15169-2mg
Description: DS-437 is a dual PRMT5/7 inhibitor with IC50 values of 6 µM and also inhibits DNMT3A and DNMT3B with IC50 values of 52 µM and 62 µM, respectively. Additionally, DS-437 inhibits the methylation of FOXP3. Target: Others. Smiles: CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12. References: Smil...
| Anwendung: | PRMT5 / PRMT7 dual inhibitor |
| CAS | 1674364-87-4 |
| MW: | 397.45 D |
41,00 €
