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JZP 430
JZP 430

Artikelnummer: Cay35383-5

JZP 430 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 0.044 for the human enzyme). It is selective for ABHD6 over fatty acid amid hydrolase (FAAH) and monoacylglycerol lipase (MAGL) when used at a concentration of 2.5 µM, ABHD12 at 1 µM, as well as lysosomal acid lipase (LAL) and...
Schlagworte: N-cyclooctyl-N-methyl-carbamic acid, 4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl ester
Anwendung: ABHD6 inhibitor
CAS 1672691-74-5
MW: 354.5 D
ab 181,00 €
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JZP-430
JZP-430

Artikelnummer: TGM-T15635-100mg

Description: JZP-430 is an effective, highly selective, irreversible inhibitor of alpha/beta-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). Target: MAGL, Lipase. Smiles: CN(C1CCCCCCC1)C(=O)Oc1nsnc1N1CCOCC1....
Anwendung: ABHD6 inhibitor
CAS 1672691-74-5
MW: 354.47 D
ab 39,00 €
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