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SD 169
Artikelnummer: Cay14156-5
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested in vitro at 50 µM. SD 169 is orally active, significantly...
| Schlagworte: | 5-Carbamoylindole, 1H-indole-5-carboxamide |
| Anwendung: | MAP kinase p38alpha / p38beta inhibitor |
| CAS | 1670-87-7 |
| MW: | 160.2 D |
ab 50,00 €
SD-169
Artikelnummer: SYN-1079-M001
Soluble in DMSO or ethanol. SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38alpha MAP kinase (IC(50) of 3.2nM) over p38beta MAP kinase (IC(50) of 122nM). Target: MAPK - p38 , Kinase Group: CMGC , Substrate:...
| Schlagworte: | SD169 |
| Anwendung: | p38 alpha inhibitor |
| CAS | 1670-87-7 |
| MW: | 160,2 D |
ab 66,00 €
